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There are many diseases associated with ageing – cancer, cardiovascular disease, type 2 diabetes, respiratory impairment, muscle wasting and neurodegenerative disease being the principal ones. Some scientists such as Jay Olshansky (University of Illinois) have made the point that if the fundamental biological pathways involved in ageing could be altered, manipulated, blocked or substituted, then all age-associated diseases could be addressed in one fell swoop. Mellon, Jim; Al Chalabi. Juvenescence: Investing in the age of longevity (Kindle Locations 649-652). Harriman House. Kindle Edition.
It appears that resveratrol and metformin have an effect in suppressing inflammaging. Resveratrol seems to dampen the effects of inflammaging by activating the gene Sirt1, leading to the deacetylation of NF-κB and down-regulation of TNF (tumour necrosis factor) alpha-induced inflammatory responses. It also seems that zinc, flavonoids, and icariin are candidates to treat inflammaging. A drug that could interfere with the gene Cdc42 (cell division control protein), which is heavily implicated. Mellon, Jim; Al Chalabi. Juvenescence: Investing in the age of longevity (Kindle Locations 1058-1060). Harriman House. Kindle Edition.
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Testing excerpt on List view small font.... Regular use of antioxidants such as magnesium, vitamin E, vitamin A, and vitamin C can lower oxidized cholesterol levels because they deal with the toxins that overload the body and spill into the cholesterol pool. Dean Md Nd, Carolyn. The Magnesium Miracle (Second Edition) (p. 171). Random House Publishing Group. Kindle Edition.
Another important mineral in the cholesterol story is copper. Copper deficiency contributes to elevated cholesterol... Dean Md Nd, Carolyn. The Magnesium Miracle (Second Edition) (p. 171). Random House Publishing Group. Kindle Edition.